Sepsis is the systemic response of the body to a bacterial infection which can result from the transfusion of a contaminated blood component. Onset is often sudden and severe. Early symptoms can include fever and chills, and as the sepsis progresses can include tachycardia, respiration problems and hypotension. A septic shock can cause the death of a patient. Confirmation of a bacterial sepsis is performed by identification of the bacteria in culture assays from blood, urine or other material.